Platelet rich plasma therapy reviews ppt
Platelet-rich plasma (PRP) is a type of cellular therapy that falls under regenerative medicine. There has been growing interest and research in using PRP injections to treat pain and promote tissue healing for musculoskeletal conditions, as well as skin rejuvenation, treatment for hair loss, breast augmentation, and wound rejuvenation. The addition of PRP to a site is believed to initiate tissue repair through a natural healing response to tissue stimulation, synthesis of new connective tissues, and revascularisation. Due to the use of autologous blood, there are limited adverse reactions compared to other injection-based therapies, such as corticosteroid injections. Show PRP is typically classified into 3 groups:
Indication[edit | edit source] Some studies have found PRP to be more beneficial in the treatment of osteoarthritis (OA) compared to saline, hyaluronic acid, or corticosteroids. Tendinopathy disorders that have also demonstrated good results from PRP in clinical trials for rotator cuff disorders, gluteal tendinopathy, and . Achilles Tendinopathy: A 2019 meta-analysis assessed 5 randomised controlled trials that examined the effect of PRP on Achilles tendinopathy compared to placebo treatment. The only significant difference was found at 6 weeks post-treatment for higher function in the PRP group compared to the placebo group. However, further follow-ups showed no significant difference between groups. Knee Osteoarthritis: A 2019 systematic review and meta-analysis examined the effects of PRP and hyaluronic acid treatments in knee OA. The review compared 18 randomised controlled trials. The PRP groups found larger improvements in short term and long term outcome measures compared to the hyaluronic acid groups. The amount of injections and formulas used varied between trials. LP-PRP injections are recommended in some systematic reviews as the preferred type of injection. A randomised controlled trial was done in Australia to evaluate the effects of intra-articular PRP injections on symptoms and joint structure in 288 patients with symptomatic mild to moderate radiographic medial knee OA . The findings did not support the use of PRP for the management of knee OA. In patients experiencing mild to moderate knee osteoarthritis with symptoms, the injection of platelet-rich plasma (PRP) into the joint, when compared to a saline placebo injection, did not lead to a notable disparity in symptoms or the condition of the joint after 12 months. Ankle Osteoarthritis: A randomised controlled trial was done in 2018-2020 in the Netherlands to investigate the effects of intra-articular PRP injections on improving ankle symptoms and function in 100 patients with ankle osteoarthritis. The study found that intra-articular PRP injections, compared with placebo injections, did not significantly improve ankle symptoms and function over 26 weeks . Lateral Epicondylalgia: Randomised control trials show better improvements in pain and function for long term results from PRP injections compared to steroid injections. Ulnar Collateral Ligament Tear (UCL): Partial and complete tears of the UCL are commonly seen in overhead athlete sports, such as baseball. Case series report good functional outcomes and return to sport with the combination of PRP and physical therapies. Contraindications[edit | edit source]Contraindications for PRP therapy include:
Procedure[edit | edit source]For the procedure, blood is collected from a patient and placed into a centrifuge to separate the blood into its components. A portion of the sample is then injected into the targeted site. There is not currently a recognized standard for the ideal formula of PRP, platelets, white blood cells, and other growth factors in the final concentration used. Post-Procedure[edit | edit source]Depending on the location of the PRP injection, physicians may have a specific post-procedure protocol depending on the location and type of injection. This can include periods of immobilization or altered weight-bearing status before gradual progression back to function and/or sport. Post-procedure protocols have not been addressed in the available research. Patients may be recommended to stop taking NSAIDS in the initial post-procedure healing phase to not hinder the pro-inflammatory goal of PRP injections. Resources[edit | edit source] References[edit | edit source]
Is PRP really worth it?“Research shows that PRP not only decreases hair shedding and stimulates new hair growth, but it also increases the thickness of the hair follicle itself. That's a huge win for many of my patients. I find myself recommending and performing hair PRP about five times per day at the office. What is PRP success rate?In fact, many global studies prove that PRP therapy is considered one of the most successful non-surgical hair loss treatment methods, with a success rate of 80-92 per cent in India. This is because the procedure is typically very safe and effective. How much does platelet rich plasma therapy cost?PRP therapy prices vary in the UK. You may pay between £250 and £500 for each session, though some clinics offer special deals if you book a course of multiple sessions. How long does it take to recover from platelet rich plasma?This is because patients will only experience minimal pain and the PRP injection recovery time is quick. Once you complete the series of injections, the general healing period is four to six weeks. Physical therapy may be recommended to you by your doctor when you hit the 5-week mark to aid your long-term healing. |